Epidermolysis Bullosa

Epidermolysis bullosa (EB) is a group of rare genetic skin disorders that causes extreme fragility of the skin, causing it to blister or tear easily in response to minor trauma or friction. With this condition, the skin is so fragile that even slight rubbing, pressure, or injury can cause painful blisters and sores. In severe cases, blisters may form spontaneously.

Severity

While painful, Epidermolysis Bullosa is not life-threatening, and blisters may become less frequent with age but can still be triggered by activities involving friction.

Affected Demographic

Epidermolysis Bullosa is most likely to have onset in the early infancy stages and often occurs more in people with a genetic predisposition to the disorder.

Treatment

While EB does not have a cure, it is treatable that allows patients to prevent the formation of blisters, treat painful blisters, and manage pain. To prevent pain after the formation of blisters, patients can avoid hot environments, wear looser clothing, and apply sunscreen and non-adhesive bandages. Doctors may also prescribe daily ointments, pain medications, antibiotic creams, and wound coverings for unhealed sores. Seeing a dermatologist is imperative for proper treatment.

Sources

1. “What Is DEB?: VYJUVEK® (Beremagene Geperpavec-Svdt).” VYJUVEK® (Beremagene Geperpavec-Svdt) - Official Website, 23 May 2024, www.vyjuvek.com/about-deb/?gad_source=1.

2. “What Is EB?” EB Research Partnership, www.ebresearch.org/what-is-eb.html?gad_source=1.

3. “Epidermolysis Bullosa: Symptoms, Causes, Types & Treatment.” Cleveland Clinic, 1 May 2024, my.clevelandclinic.org/health/diseases/17792-epidermolysis-bullosa.